Grand Island is a city in and the county seat of Hall County, Nebraska, United States. The population was 48,520 at the 2010 census.

Grand Island was a long wooded island near Grand Island, Nebraska. The island was known by French traders as La Grande Isle. Grand Island was formed by the Wood River and a channel of the Platte River. It was the original location of Grand Island, Nebraska, but the town was later moved north of the Wood River. Settlers intending to create a settlement there arrived on July 4, 1857, and by September had built housing using local timber. The island no longer exists as the Wood River no longer has a western connection to the Platte.

Grand Island ist eine Stadt im Zentrum des US-Bundesstaates Nebraska und gleichzeitig dessen drittgrößte Stadt. Im Jahr 2000 hatte die Stadt 42.940 Einwohner. Nach der Fortschreibung wohnten 2006 hier 44.632 Personen. Die Stadt ist County Seat des Hall Countys und wichtigster Ort der Grand Island Micropolitan Statistical Area, die außer dem Hall County auch Merrick County und Howard umfasst.